研究

1. 新型小分子 anthraquinone 衍生物之細胞週期及程式死亡訊息標靶活性之研究(1/3)
   國科會99年度專題研究計畫(99/08/01~100/07/31)
2. 新型小分子 anthraquinone 衍生物之細胞週期及程式死亡訊息標靶活性之研究(2/3)
   國科會100年度專題研究計畫(100/08/01~101/07/31)
3. 新型小分子 anthraquinone 衍生物之細胞週期及程式死亡訊息標靶活性之研究(3/3)
   國科會101年度專題研究計畫(101/08/01~103/07/31)
4. 植物水萃取之育髮活性評估；產學計畫 (103/10/10~106/01/31)
5. 植物萃取物之毒性試驗；產學計畫 (104/12/01~107/12/31)
6. 植物水萃物之抗癌活性與毒性之評估；產學計畫 (106/6/15~108/12/31)
7. 牛樟木培育之牛樟菇酒精萃取物生物活性與毒性之評估；產學計畫 (107/6/20~109/12/31)

著作

1. Tsai SS, Chiu HF, Yang CY*.  Ambient Air Pollution and Hospital Admissions for Peptic Ulcers in Taipei: A Time-Stratified Case-Crossover Study.  Int J Environ Res Public Health. 2019 May 30;16(11). 
2. Yang CY, Huang YT, Chiu HF*. Does ambient ozone air pollution trigger suicide attempts? A case cross-over analysis in Taipei. J Toxicol Environ Health A. 2019;82(10):638-644. 
3. Ou YJ, Chiu HF, Wong YH, Yang CC, Yang YH. Bisphosphonate use and the risk of breast cancer: a meta-analysis of observational studies. Pharmacoepidemiol Drug Saf. 2017 Oct;26(10):1286-1295.
4. Chiu HF, Tsai SS, Yang CY. Short-term effects of fine particulate air pollution on hospital admissions for hypertension: A time-stratified case-crossover study in Taipei. J Toxicol Environ Health A. 2017;80(5):258-265.
5. Chiu HF, Weng YH, Chiu YW, Yang CY. Short-term effects of ozone air pollution on hospital admissions for myocardial infarction: A time-stratified case-crossover study in Taipei. J Toxicol Environ Health A. 2017;80(5):251-257. 
6. Cheng MH, Wong YH, Chang CM, Yang CC, Chen SH, Yuan CL, Kuo HM, Yang CY, Chiu HF. B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB. Int J Mol Med. 2017 May;39(5):1137-1148. 
7. Chiu HF, Chen BK, Yang CY. Parity, Age at First Birth, and Risk of Death from Bladder Cancer: A Population-Based Cohort Study in Taiwan. Int J Environ Res Public Health. 2016 Dec 2;13(12). 
8. Chen CC, Chiu HF, Yang CY. Air pollution exposure and daily clinical visits for allergic rhinitis in a subtropical city: Taipei, Taiwan.J Toxicol Environ Health A. 2016;79(12):494-501.
9. Chen BK, Chiu HF, Yang CY. Statins are Associated With a Reduced Risk of Brain Cancer: A Population-Based Case-Control Study. Medicine (Baltimore). 2016 Apr;95(17):e3392. 
10. Cheng MH, Chiu HF, Yang CY. The Effects of Coarse Particles on Daily Mortality: A Case-Crossover Study in a Subtropical City, Taipei, Taiwan. Int J Environ Res Public Health. 2016 Mar 22;13(3).
11. Cheng MH, Chiu HF, Yang CY. Coarse Particulate Air Pollution Associated with Increased Risk of Hospital Admissions for Respiratory Diseases in a Tropical City, Kaohsiung, Taiwan. Int J Environ Res Public Health. 2015 Oct 16;12(10):13053-68.
12. Chang CC, Chiu HF, Yang CY.Fine particulate air pollution and outpatient department visits for headache in taipei, taiwan. J Toxicol Environ Health A. 2015;78(8):506-15.
13. Chiu HF, Yang CY.Air pollution and daily clinic visits for migraine in a subtropical city: taipei, taiwan. J Toxicol Environ Health A. 2015;78(9):549-58.
14. Chiu HF, Weng YH, Chiu YW, Yang CY. Air pollution and daily clinic visits for headache in a subtropical city: Taipei, Taiwan. Int J Environ Res Public Health. 2015 Feb 17;12(2):2277-88.
15. Chan TF, Wu CH, Chiu HF, Yang CY.  Parity and risk of death from gallbladder cancer among a cohort of premenopausal parous women in Taiwan. Int J Environ Res Public Health. 2015 Feb 5;12(2):1864-73.
16. Chen CC, Chiu HF, Yang CY. Parity, age at first birth, and risk of death from asthma: evidence from a cohort in taiwan. Int J Environ Res Public Health. 2014 Jun 11;11(6):6147-55.
17. Cheng MH, Chen CC, Chiu HF, Yang CY. Fine particulate air pollution and hospital admissions for asthma: a case-crossover study in Taipei. J Toxicol Environ Health A. 2014;77(18):1075-83.
18. Tsai SS, Chiu HF , Liou SH, Yang CY. Short-term effects of fine particulate air pollution on hospital admissions for respiratory diseases: a case-crossover study in a tropical city. J Toxicol Environ Health A. 2014; 77(18):1091-101.
19. Chiu HF, Chang CC, Yang CY. Relationship between hemorrhagic stroke hospitalization and exposure to fine particulate air pollution in Taipei, Taiwan. J Toxicol Environ Health A. 2014; 77(19):1154-63.
20. Lin HC, Chiu HF , Ho SC, Yang CY. Association of influenza vaccination and reduced risk of stroke hospitalization among the elderly: a population-based case-control study. Int J Environ Res Public Health. 2014 Apr 2;11(4):3639-49.
21. Yang YC, Wei MC, Chiu HF , Huang TC. Development and validation of a modified ultrasound-assisted extraction method and a HPLC method for the quantitative determination of two triterpenic acids in Hedyotis diffusa. Nat Prod Commun. 2013 Dec;8(12):1683-6.
22. Chiu HF, Yang CY. Short-term effects of fine particulate air pollution on ischemic stroke occurrence: a case-crossover study. J Toxicol Environ Health A. 2013; 76(21):1188-97.
23. Wei MC, Yang YC, Chiu HF , Hong SJ. Development of a hyphenated procedure of heat-reflux and ultrasound-assisted extraction followed by RP-HPLC separation for the determination of three flavonoids content in Scutellaria barbata D. Don. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec ; 940:126-34.
24. Liao YH, Chen PS, Chiu HF, Yang CY. Magnesium in drinking water modifies the association between nitrate ingestion and risk of death from esophageal cancer. J Toxicol Environ Health A. 2013; 76(3):192-200.
25. Chan TF, Chiu HF, Wu CH, Lin CL, Yang CY. Statin use and the risk of esophageal cancer: a population-based case-control study. Expert Opin Drug Saf. 2013 May;12(3):293-8.
26. Chiu HF , Chen BK, Yang CY. Herpes zoster and subsequent risk of cancer: a population-based study. J Epidemiol. 2013;23(3):205-10.
27. Chiu HF, Kuo CC, Kuo HW, Lee IM, Yang CY. Parity, age at first birth and risk of death from kidney cancer: a population-based cohort study in Taiwan. Eur J Public Health. 2013 Jun 6. [Epub ahead of print]
28. Chiu HF, Tsai SS, Weng HH, Yang CY. Short-term effects of fine particulate air pollution on emergency room visits for cardiac arrhythmias: a case-crossover study in taipei. J Toxicol Environ Health A. 2013 May;76(10):614-23.
29. Tsai SS, Chiu HF, Yang CY. Trihalomethanes in drinking water and the risk of death from esophageal cancer: does hardness in drinking water matter? J Toxicol Environ Health A. 2013;76(2):120-30.
30. Cheng MH, Chiu HF, Tsai SS, Chen CC, Yang CY. Calcium and magnesium in drinking-water and risk of death from lung cancer in women. Magnes Res. 2012 Jul-Sep;25(3):112-9.
31. Chiu HF , Chen CC, Tsai SS, Ho SC, Yang CY. Parity, age at first birth, and risk of death from brain cancer: a population-based cohort study in Taiwan. BMC Public Health. 2012 Oct 9;12:857. doi: 10.1186/1471-2458-12-857.
32. Kuo CC, Chiu HF, Lee IM, Kuo HW, Lee CT, Yang CY. Statin use and the risk of bladder cancer: a population-based case-control study. Expert Opin Drug Saf. 2012 Sep;11(5):733-8.
33. Chiu HF, Kuo CC, Kuo HW, Lee IM, Lee CT, Yang CY. Statin use and the risk of kidney cancer: a population-based case-control study. Expert Opin Drug Saf. 2012 Jul;11(4):543-9.
34. Chiu HF, Kuo CH, Tsai SS, Chen CC, Wu DC, Wu TN, Yang CY. Effect modification by drinking water hardness of the association between nitrate levels and gastric cancer: evidence from an ecological study. J Toxicol Environ Health A. 2012 Jun 15;75(12):684-93.
35. Cheng MH, Tsai SS, Chen CC, Ho SC, Chiu HF, Wu TN, Yang CY. Parity and risk of death from lung cancer among a cohort of premenopausal parous women in taiwan. J Epidemiol. 2012 Jul 5;22(4):364-9.
36. Liao YH, Chen CC, Chang CC, Peng CY, Chiu HF, Wu TN, Yang CY. Trihalomethanes in drinking water and the risk of death from kidney cancer: does hardness in drinking water matter?J Toxicol Environ Health A. 2012 Mar 15;75(6):340-50.
37. Cheng MH, Chiu HF, Ho SC, Yang CY. Statin use and the risk of female lung cancer: A population-based case-control study. Lung Cancer. 2012 Sep 27;75(3):275-9.
38. Chiu HF, Chen CC, Kuo HW, Lee IM, Wu TN, Yang CY. Statin use and the risk of gallstone disease: a population-based case-control study. Expert Opin Drug Saf. 2012 May;11(3):369-74.
39. Chang CC, Chiu JJ, Chen SL, Huang HC, Chiu HF , Lin BH, Yang CY. The activation of HGF/c-Met signaling by ultrafine carbon particles and its contribution to alveolar type II cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2012 Apr; 302(8): L755-63.
40. Hung LJ, Chan TF, Wu CH, Chiu HF, Yang CY. Traffic air pollution and risk of death from ovarian cancer in Taiwan: fine particulate matter (PM2.5) as a proxy marker. J Toxicol Environ Health A. 2012 Feb 1;75(3):174-82.
41. Chiu HF, Tsai SS, Chen PS, Wu TN, Yang CY. Does calcium in drinking water modify the association between nitrate in drinking water and risk of death from colon cancer? J Water Health. 2011 Sep;9(3):498-506.
42. Cheng MH, Chiu HF, Ho SC, Tsai SS, Wu TN, Yang CY. Statin use and the risk of colorectal cancer: a population-based case-control study. World J Gastroenterol. 2011 Dec 21;17(47):5197-202.
43. Chang CC, Chen CY, Chiu HF, Dai SX, Liu MY, Yang CY. Elastases from inflammatory and dendritic cells mediate ultrafine carbon black induced acute lung destruction in mice. Inhal Toxicol. 2011 Aug;23(10):616-26.
44. Chiu HF, Ho SC, Chang CC, Wu TN, Yang CY. Statins Are Associated With a Reduced Risk of Gastric Cancer: A Population-Based Case-Control Study. Am J Gastroenterol. 2011 Aug 16. doi: 10.1038/ajg.2011.277.
45. Chiu HF, Tsai SS, Chen PS, Liao YH, Liou SH, Wu TN, Yang CY. Traffic air pollution and risk of death from gastric cancer in Taiwan: petrol station density as an indicator of air pollutant exposure. J Toxicol Environ Health A. 2011 Sep 15;74(18):1215-24.
46. Chiu HF , Chang CC, Ho SC, Wu TN, Yang CY. Statin use and the risk of pancreatic cancer: a population-based case-control study. Pancreas. 2011 Jul;40(5):669-72.
47. Chang CC, Ho SC, Chiu HF, Yang CY. Statins increase the risk of prostate cancer: A population-based case-control study. Prostate. 2011 Apr 7. doi: 10.1002/pros.21401.
48. Chang CC, Chen CC, Chiu HF, Yang CY. Higher parity associated with higher risk of death from gastric cancer.World J Gastroenterol. 2011 Feb 14;17(6):784-8.
49. Chiu HF , Ho SC, Chen CC, Yang CY. Statin use and the risk of liver cancer: a population-based case–control study. Am J Gastroenterol. 2011 May;106(5):894-8.
50. Chiu HF , Chang CC, Chen CC, Yang CY. Calcium and magnesium in drinking water and risk of death from kidney cancer. J Toxicol Environ Health A. 2011;74(1):62-70.
51. Chiu HF, Tsai SS, Wu TN, Yang CY. Effect modification of the association between trihalomethanes and pancreatic cancer by drinking water hardness: evidence from an ecological study. Environ Res. 2010 ;110(5):513-8.
52. Chiu HF, Tsai SS, Wu TN, Yang CY. Colon cancer and content of nitrates and magnesium in drinking water. Magnes Res. 2010; 23(2):81-9.
53. Chang CC, Chiu HF , Yang CY. Parity, age at first birth, and risk of death from pancreatic cancer: evidence from a cohort in Taiwan. Pancreas. 2010 ;39(5):567-71.
54. Chiu HF, Yang CY. Air pollution and emergency room visits for arrhythmias: are there potentially sensitive groups? J Toxicol Environ Health A. 2009;72(13):817-23.
55. Chang CC, Tsai SS, Chiu HF, Wu TN, Yang CY. Traffic air pollution and lung cancer in females in Taiwan: petrol station density as an indicator of disease development. J Toxicol Environ Health A. 2009;72(10):651-7.
56. Yang CY, Tsai SS, Chiu HF* . Nitrate in drinking water and risk of death from pancreatic cancer in Taiwan. J Toxicol Environ Health A. 2009;72(6):397-401.

研討會論文

1. Yang CC, Wong YH, Lin WT, Valens Munyembaraga, Lin YC, Tina YH, Yang YC, Hong SJ, Chang HM, Chiu HF*. Anandamide Induced Hepatoma Cell Apoptosis May through Epigenetic HDAC Regulation. (2019) The 34th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. (Poster)
2. Lin WT, Wong YH, Valens Munyembaraga, Lin YC, Yang CC, Chen YC, Yang YC, Hong SJ, Chiu HF*. (2018) Fucoidan Induced Cell Apoptosis may through Generation of ROS and Disruption of Mitochondrial Membrane Potential in Human Renal Cancer Cells.  The 33th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. (Poster)
3. Yang CC, Chang CM, Wong YH, Cheng MH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chiu HF*. 18th World Congress of Basic and Clinical Pharmacology (WCP 2018) . Japan/Kyoto. (Poster)
4. Lin YC, Wong YH, Valens Munyembaraga, Lin WT, Chen YC, Yang YC, Chiu HF*. (2018) Fucoidan Induced Apoptosis may through STAT3 and NF-κB Regulation in Human Lung Cancer Cells.  The 33th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. (Poster)
5. Wong YH, Cheng MH, Yang CC, Chu YC, Lin YC, Ou YJ, Lin WT, Chen SH, Chiang YW, Chang CM, Yu TH, Kuo HM, Chiu HF*. (2017) Bullatacin Induces Cell Cycle Arrest and Apoptosis in Human Hepatoma Cell may through the Modulation of JAK2 and STAT3. 16th Meeting of the Consortium for Globalization of Chinese Medicine. China /Guangzhou (Poster)
6. Yang CC, Wong YH, Cheng MH, Chu YC, Chang CM, Lin WT, Lin YC, Chiu HF*. (2017) Anandamide induced cell cycle arrest and apoptosis induction in lung cancer cells lines. The 32th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. p:589;2017. (Poster)
7. Chu YC, Wong YH, Lin YC, Cheng MH, Yang CC, Ou YJ, Lin WT, Tian YH, Kuo HM, Chung MI, Chiu HF*. (2017) Fucoidan Induced Cell Cycle Arrest in Human Hepatoma Cells May through the Regulation of STAT3. 16th Meeting of the Consortium for Globalization of Chinese Medicine. China /Guangzhou (Poster)
8. Wong YH, Chu YC, Cheng MH, Yang CC, Chang CM, Lin WT, Lin YC, Yu TH, Chiu HF*. (2017) Bullatacin, a potent cytotoxic Annonaceous autogenin, induced cell cycle arrest and migration attention in human hepatoma cells. The 32th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. p:590;2017. (Poster)
9. Chu YC, Lin YC, Wong YH, Yang CC, Cheng MH, Chang CM, Lin WT, Tian YH, Chiu HF*. (2017) Fucoidan, an extract from brown seaweed, induced cell cycle arrest and apoptotic induced in A549 lung cancer cells. The 32th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. p:591;2017. (Poster)
10. Lin YC, Chang CM, Cheng MH, Yang CC, Wong YH, Yuan CL, Kuo HM, Chiu HF*. (2016) Fucoidan, an extract from brown seaweed, attenuates migration and induces apoptotic cell death in A549 lung cancer cells. 15th Meeting of Consortium for Globalization of Chinese Medicine. Taiwan/Taipei (Poster)
11. Yang CC,Chang CM , Wong YH, Cheng MH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chen CY, Chiu HF*. (2016) Anandamide Induced Human Hepatoma Cells death through the DNA Damage and Apoptosis Induction. 15th Meeting of Consortium for Globalization of Chinese Medicine. Taiwan/Taipei (Poster)
12. Wong YH, Cheng MH, Yang CC, Chang CM, Lin YC, Yuan CL, Kuo HM, Chiu HF*. (2016) The Effect of C-Phycocyanin on Cell Cycle Arrest and Apoptosis Induction through the Regulation of STAT3 and NFκB in Human Hepatoma Cells. 15th Meeting of Consortium for Globalization of Chinese Medicine. Taiwan/Taipei (Poster)
13. Yang CC , Chang CM,  Wong YH, Cheng MH, Yang YC , Kuo HM, Yuan CL, Hong SJ , Chen CY , Chiu HF*.  (2016) Anandamide induced autophagy and apoptosis in human hepatoma cells. The 31th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
14. Yang CC, Chang CM, Lee CW, Wu KH, Wong YH, Cheng MH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chen CY, Chiu HF*.(2015) Anandamide Induced Cell Cycle arrest through the DNA Damage and inhibition of telomerase activity in Human Hepatoma Cells. The 30^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
15. Yang CC, Chang CM, Chen CY, Wong YH, Cheng MH, Lin TH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chiu HF*. (2015) Anandamide Induced Apoptosis through the ROS Generation and DNA Damage in Human Hepatoma Cells. The 29^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
16. Chen CY, Chang CM, Yang CC, Wong YH, Cheng MH, Yu TH, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2014) C-phycocyanin induced Anti-proliferation and Angiogenesis Repression in Human Hepatoma Cell. The 29^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
17. Chang CM, Chen CY, Yang CC, Wong YH, Cheng MH, Yang IN, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2014) B7, A Novel Anthraquinone Derivative, Cause Cell Cycle G1 Arrest through Cyclin D/E and Cyclin Dependent Kinases 2/4 (CDK 2/4) inhibition in Human Hepatoma Cells. The 29^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
18. Cheng MH, Chang CM, Chen CY, Yang CC, Liao KH, Wong YH, Chen SH, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*.(2014) B1, A Novel Telomerase Inhibitor, Induces DNA Double Strand Break and Represses Angiogenesis in Human Lung Cancer Cells. The 29^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
19. Chiang YW, Chen SH, Chang CM, Wong YH, Cheng MH, Chen CY, KH Liao, Yang CC, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2013) Bullatacin Induces Apoptosis Through the Regulation of Fas, Caspase8/9 and Bax/Bcl-2 Protein Expression in Human Hepatoma Cell. The 28^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
20. Yang CC, Yang YC, Cheng MH, Wong YH, Chen SH, Chiang YW, Chang CM, Chen CY, Kuo HM, Yuan CL, Chiu HF*. (2013) The Regulation of the STAT3 in AEA Induced Hepatoma Cell Apoptosis. The 28^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
21. Wong YH, Yang YC, Lee CY, Cheng MH, Yang CC, Chen SH, Chang CM, Yuan CL, Kuo HM, Wang FJ, Chiu HF*. (2012) The Anti-proliferation and Anti-angiogenesis Effects of Fucoidan in Cancer Cells. The 27^th Joint Annual Conference of Biomedical Sciences. Taiwan/Taipei (Poster presentation)
22. Yang CY, Tsai SS, Chang CC, Chiu HF. (2012) Effect modification of the association between trihalomethanes and pancreatic cancer by drinking water hardness: Evidence from an ecological study. 24th International Society for Environmental Epidemiology (ISEE) conference. United States of America/ Columbia, South Carolina (Poster presentation)

指導研究生

校內外榮譽

1. 100 學年度本校研究績優教師
2. 100 學年度本校研究論文獎勵
3. 100 學年度科技部補助大專校院獎勵特殊優秀人才
4. 101 學年度科技部補助大專校院獎勵特殊優秀人才
5. 102 學年度科技部補助大專校院獎勵特殊優秀人才
6. 103 學年度產學合作績優獎
7. 104 學年度產學合作績優獎
8. 105 學年度產學合作績優獎
9. 105 學年度教師教學評量優良(有效平均值 5.0~5.429)
10. 106 學年度產學合作優良獎
11. 107-2 課程評量績優(有效平均值 5.40 分（含）以上)
12. 榮獲109年資深優良教師總統獎
13. 109 學年度產學合作績優獎