洪秀貞 教授

- 電話:+886-7-3121101 ext.2139,2243 #12、15
- 傳真:+886-7-3234686
- 信箱:showjen@kmu.edu.tw
- 學歷:
- 高雄醫學大學 醫學研究所 博士
- 陽明大學 神經科學研究所 碩士
- 高雄醫學大學 藥學系 學士
- 研究方向:
- 青光眼用藥及應用
教學
主負責專業課程
- 碩士班一年級:藥理學訊號特論、眼科藥理學與治療學特論
參與其他專業課程
- 大學部醫學系、後醫學系:block 課程
- 大學部牙醫學系三年級:藥理學(含牙科藥理學)、藥理學實驗
- 大學部藥學系二年級:藥理學、藥理學實驗
- 大學部護理系二年級:藥理學
著作
- Yang YC, Wei MC, Hong SJ*. Evaluation of occupation hot exposure in industrial workplaces in a subtropical country. Int J Occup Med Environ Health. 2017 May 8;30(3):379-395.
- Wu KY, Lai YH, Yang YC, Wu WC, Hong SJ*. 5-Fluorouracil-Induced Apoptosis Changes in Cultured Corneal Epithelial Cells. J Ocul Pharmacol Ther. 2016 Apr;32(3):155-62.
- Wei MC, Yang YC*, Hong SJ. Determination of Oleanolic and Ursolic Acids in Hedyotis diffusa Using Hyphenated Ultrasound-Assisted Supercritical Carbon Dioxide Extraction and Chromatography. Evid Based Complement Alternat Med. 2015; 2015:450547.
- Hong SJ, Wu WC, Lai YH, Wu KY*. Mechanism of 5-Fluorouracil-Induced Apoptosis on Culutred corneal Ednothelail Cells. Open Journal oa Apoptosis. 2014 Apr; 3:5-15.
- Yang YC, Wei MC, Hong SJ. Ultrasound-assisted extraction and quantitation of oils from Syzygium aromaticum flower bud (clove) with supercritical carbon dioxide. J Chromatogr A. 2014 Jan 3;1323:18-27.
- Wei MC, Yang YC, Chiu HF, Hong SJ. Development of a hyphenated procedure of heat-reflux and ultrasound-assisted extraction followed by RP-HPLC separation for the determination of three flavonoids content in Scutellaria barbata D. Don. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 1;940:126-34.
- Wu KY, Wu PC, Lai YH, *Hong SJ. Novel usage of intraocular pressure-lowering drugs as wound-healing inhibitors after trabeculectomy with cell culture and animal models. Kaohsiung J Med Sci. 2013 Jul;29 (7):353-61.
- Yang YC, Wei MC*, Hong SJ, Huang TC, Lee SZ. Development/optimization of a green procedure withultrasound-assisted improved supercritical carbon dioxide to produceextracts enriched in oleanolic acid and ursolic acid from Scutellariabarbata D. Don. Industrial Crops and Products. 2013 Jul; 49(1):542-553.
- Wu KY, Chang CH, Wang HZ, *Hong SJ. Mechanism of carteolol-induced cytosolic Ca(2+) mobilization in cultured vascular smooth muscle cells. Vascular Pharmacology. 04, 003, 1-6, 2010.
- Wu KY, Wang HZ, *Hong SJ. Mechanism of mitomycin-induced apoptosis in cultured corneal endothelial cells. Mol Vis. 2008 Sep 15;14:1705-12.
- Wu KY , Wang HZ, *Hong SJ: Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells. Kaohsiung J Med Sci 23: 105-111, 2007.
- Wu KY , Wang HZ and *Hong SJ: Mechanism of unoprostone-induced cytosolic Ca2+ mobility in cultured porcine corneal endothelial cells. Exp Eye Res 85: 185-191, 2007. (NSC94-2314-B-037-080) and (NHRI-EX95-9213SI)
- Wu KY , Wang HZ and *Hong SJ: The cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells. Kaohsiung J Med Sci 22: 120-125, 2006. (NSC92-2320-B-037-034) and (NHRI-EX94-9213SI)
- Wu KY , Wang HZ and *Hong SJ: Effects of antiglaucoma drugs on cellular proliferation in cultured human corneal keratocytes. Kaohsiung J Med Sci 22:120-125, 2006 (NSC89-2314-B-037-148) and (NHRI-EX94-9213SI)
- Wu KY , Hong SJ and Wang HZ: Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells. Kaohsiung J Med Sci 22:60-67, 2006 (NSC92-2320-B-037-034) and (NHRI-EX94-9213SI)
- Wu KY , Wang HZ and *Hong SJ: Effects of antibiotics and corticosteroids eyedrops on cellular proliferation in cultured human corneal keratocytes. Kaohsiung J Med Sci 22:385-389, 2006 (NSC93-2314-B-037-032) and (NHRI-EX95-9213SI).
研討會論文
.- Wei-Tung Lin, Yun-Hong Wong, Valens Munyembaraga, Yu-Chieh Lin, Chun-Chien Yang, Yung-Chia Chen, Yu-Chaio Yang, Show-Jan Hong, Hui-Fen Chiu*. (2018) Fucoidan Induced Cell Apoptosis may through Generation of ROS and Disruption of Mitochondrial Membrane Potential in Human Renal Cancer Cells. The 33th Joint Annual Conference of Biomedical Science, Taipei,Taiwan. (Poster)
- Ming-Chi Wei, Show-Jen Hong, Hui-fen Chiu, Pei-Hui Lin and Yu-Chiao Yang*. (2018) Development and Validation of a Green Procedure for Production of three Key Bioactive Compounds from a Herbal Tea. European Biological Inorganic Chemistry Conference. 英國/伯明翰. (Invited Speaker)
- Chun-Chien Yang, Chia-Ming Chang, Yun-Hong Wong, Meng-Hsuan Cheng, Yu-Chiao Yang, Hsiao-Mei Kuo, Chun-Lung Yuan, Show-Jen Hong, Hui-Fen Chiu*. 18th World Congress of Basic and Clinical Pharmacology (WCP 2018) . Japan/Kyoto. (Poster)
- Yang YC , Hong SJ, Lin PH, Wei MC∗. (2017). Production of eugenyl acetate-enriched oil from clove using ultrasound-assisted supercritical carbon dioxide extraction. 20th Annual Enerngy, Utility & Enviroment. United States of America/San Diego. (Invited Speaker)
- Yang YC , Hong SJ, Lin PH, Wei MC∗. (2017) Development of a green alternative procedure for simultaneous separation and quantification of phytochemicals. International Science and Technology America Conference. United States of America/Boston. (Invited Speaker)
- Wei MC, Lin PH, Hong SJ, Yang YC*.(2016) Extraction Kinetics of Ultrasound-assisted Extraction of Oleanolic Acid from Hedyotis corymbosa. 11th International Conference on Mass Data Analysis of Images and Signals
- Yang CC,Chang CM , Wong YH, Cheng MH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chen CY, Chiu HF*. (2016) Anandamide Induced Human Hepatoma Cells death through the DNA Damage and Apoptosis Induction. 15th Meeting of Consortium for Globalization of Chinese Medicine.
- Yang CC, Chang CM, Lee CW, Wu KH, Wong YH, Cheng MH, Yang YC, Kuo HM, Yuan CL, Hong SJ, Chen CY, Chiu HF*.(2015) Anandamide Induced Cell Cycle arrest through the DNA Damage and inhibition of telomerase activity in Human Hepatoma Cells. The 30th Joint Annual Conference of Biomedical Sciences. (Poster)
- Chen CY, Chang CM, Yang CC, Wong YH, Cheng MH, Yu TH, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2014) C-phycocyanin induced Anti-proliferation and Angiogenesis Repression in Human Hepatoma Cell. The 29th Joint Annual Conference of Biomedical Sciences. (Poster)
- Chang CM, Chen CY, Yang CC, Wong YH, Cheng MH, Yang IN, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2014) B7, A Novel Anthraquinone Derivative, Cause Cell Cycle G1 Arrest through Cyclin D/E and Cyclin Dependent Kinases 2/4 (CDK 2/4) inhibition in Human Hepatoma Cells. The 29th Joint Annual Conference of Biomedical Sciences. (Poster)
- Cheng MH, Chang CM, Chen CY, Yang CC, Liao KH, Wong YH, Chen SH, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*.(2014) B1, A Novel Telomerase Inhibitor, Induces DNA Double Strand Break and Represses Angiogenesis in Human Lung Cancer Cells. The 29th Joint Annual Conference of Biomedical Sciences. (Poster)
- Chiang YW, Chen SH, Chang CM, Wong YH, Cheng MH, Chen CY, KH Liao, Yang CC, Yang YC, Yuan CL, Kuo HM, Hong SJ, Chiu HF*. (2013) Bullatacin Induces Apoptosis Through the Regulation of Fas, Caspase8/9 and Bax/Bcl-2 Protein Expression in Human Hepatoma Cell. The 28th Joint Annual Conference of Biomedical Sciences. (Poster)
- Wong YH, Chen SH, Yang CC, Yang YC, Cheng MH, Chiang YW, Chang CM, Chen CY, Yang IN, Liao KH, Kuo HM, Lung YC, Hong SJ, Chiu HF*. (2013) Anandamide inhibits cell migration and angiogenesis through the regulation of MMP2/9 and VEGF. The 28th Joint Annual Conference of Biomedical Sciences. (Poster)